Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082024 | 1.00 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15081933 | 1.00 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17084067 | 0.84 | MEN1 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17084081 | 0.84 | MEN1 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17084069 | 0.84 | MEN1 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15082022 | 0.78 | GRIA2 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15081931 | 0.78 | GRIA2 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19368281 | 0.78 | SLC6A2 (0.45) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL21958842 | 0.76 | SLC6A2 (0.40) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15084372 | 0.76 | SLC6A2 (0.40) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |