SCHEMBL10211338

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15378133	0.94	TP53 (0.51)	TP53MAPTALDH1A1HPGDCYP2C9
	SCHEMBL10211674	0.90	MAPT (0.52)	TP53MAPTALDH1A1HPGDCYP2C9
	SCHEMBL10211741	0.89	MAPT (0.62)	TP53MAPTALDH1A1HPGDCYP2C9
	SCHEMBL15378459	0.89	TP53 (0.49)	TP53MAPTALDH1A1HPGDCYP2C9
	SCHEMBL10211319	0.89	MAPT (0.56)	TP53MAPTALDH1A1HPGDCYP2C9
	SCHEMBL15378410	0.88	NAMPT (0.47)	TP53MAPTALDH1A1HPGDKDM4E
	SCHEMBL9953214	0.88	TP53 (0.59)	TP53MAPTALDH1A1HPGDKDM4E
	SCHEMBL15378538	0.88	TP53 (0.64)	TP53MAPTALDH1A1HPGDCDH1
	SCHEMBL10211356	0.88	TACR3 (0.48)	TP53MAPTDRD2ALDH1A1HPGD
	SCHEMBL15377566	0.87	TP53 (0.47)	TP53MAPTALDH1A1HPGDCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.