⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459884 | 0.69 | — | — | |
| SCHEMBL7859441 | 0.69 | — | — | |
| SCHEMBL5169417 | 0.69 | — | — | |
| SCHEMBL6131433 | 0.67 | — | — | |
| SCHEMBL60166 | 0.67 | — | — | |
| SCHEMBL5170716 | 0.67 | — | — | |
| SCHEMBL9474222 | 0.67 | — | — | |
| SCHEMBL760096 | 0.67 | — | — | |
| SCHEMBL5170020 | 0.65 | — | — | |
| SCHEMBL4317948 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232117-B | Substituted isoxazole pyrimidine amine compound, preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-115232117-A | Substituted isoxazole pyrimidinamine compound and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-110872302-B | Pyrimidine-containing spiro-compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-113512029-A | Preparation and application of substituted pyrazole compound containing pyrimidinamine | 沈阳中化农药化工研发有限公司 | 2021-10-19 | — | — | CN | claimed |
| WO-2021083185-A1 | PYRIMIDINE-CONTAINING PIPERIDINAMINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2021-05-06 | — | — | WO | claimed |
| CN-112745297-A | Pyrimidine-containing piperidine amine compound and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2021-05-04 | — | — | CN | claimed |
| US-20210015100-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2021-01-21 | — | — | US | claimed |
| EP-3719015-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2020-10-07 | — | — | EP | claimed |
| CN-108069973-B | Substituted six-membered heterocyclic compound containing pyrimido ring and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-111263757-A | Substituted pyrimidine compound and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2020-06-09 | — | — | CN | claimed |
| WO-2010009139-A2 | IMIDAZOLYL PYRIMIDINE INHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-01-21 | — | — | WO | claimed |
| WO-2010009155-A2 | FUSED HETEROCYCLYC INHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-01-21 | — | — | WO | claimed |
| WO-2010003499-A2 | AGROCHEMICAL FORMULATION | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-14 | — | — | WO | claimed |
| US-20100009990-A1 | IMIDAZOLYL PYRIMIDINE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2010-01-14 | — | — | US | claimed |
| US-20090005374-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD SCIENCES, INC. | 2009-01-01 | — | — | US | claimed |
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | claimed |
| WO-2008130320-A2 | NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| WO-2008130581-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | claimed |
| EP-0302328-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-08 | — | — | EP | claimed |
| EP-0296518-A1 | Phenyl-ether derivatives, process for their preparation and application | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | claimed |