SCHEMBL1022968

SCHEMBL1022968

C=CC(=O)OCCn1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.44
ALDH1A1 P00352 5/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 1/20 0.44
HPGD P15428 1/20 0.41
THRB P10828 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.33
MAPK1 P28482 1/20 0.33
APEX1 P27695 1/20 0.33
MAPT P10636 1/20 0.32
GAA P10253 2/20 0.31
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HTT P42858 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004951 0.90 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27704679 0.89 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28004594 0.88 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL978240 0.87 APEX1 (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11904897 0.86 ATM (0.37) ALDH1A1HPGDSMN1; SMN2APEX1MAPT
SCHEMBL8417098 0.84 APEX1 (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31411950 0.83 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21816726 0.83 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27900308 0.81 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28095927 0.81 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 764 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118223302-A Biodegradable laminated cloth and preparation method thereof 浙江青云纺织科技有限公司 2024-06-21 CN claimed
CN-117987049-A Halogen-free flame-retardant acrylate adhesive for flexible printed circuit board, preparation method thereof and adhesive film 华烁电子材料(武汉)有限公司 2024-05-07 CN claimed
CN-117120488-A Radiation curable (meth) acrylic adhesive composition 汉高股份有限及两合公司 2023-11-24 CN claimed
CN-116969952-A Diphenyl pyrrolo-pyrrole-dione derivative and pigment composition thereof 山东凯瑞尔光电科技有限公司 2023-10-31 CN claimed
CN-116836200-A Double-base compound based on DOPS-triazinetrione structure, and preparation method and application thereof 贵州民族大学 2023-10-03 CN claimed
CN-116333454-A Resin composition, resin composition film and multilayer circuit board 杭州福斯特电子材料有限公司 2023-06-27 CN claimed
EP-4069792-A1 MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY fischerwerke GmbH & Co. KG (DE) 2022-10-12 EP claimed
CN-113061397-B Packaging adhesive film and photovoltaic module 福斯特(嘉兴)新材料有限公司 2022-05-31 CN claimed
CN-113061397-A Packaging adhesive film and photovoltaic module 福斯特(嘉兴)新材料有限公司 2021-07-02 CN claimed
WO-2021110621-A1 MICHAEL REACTION-CURING HYBRID SYSTEM FOR USE IN CHEMICAL FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2021-06-10 WO claimed
CN-109310890-A Composition containing latex particle and UV absorbent 罗门哈斯公司 2019-02-05 CN claimed
US-8703253-B2 Composition for liquid crystal alignment layer, preparation method of liquid crystal alignment layer using the same, and optical film comprising the liquid crystal alignment layer LG CHEM, LTD. (KR) 2014-04-22 US claimed
US-20110051050-A1 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-03-03 US claimed
EP-2158635-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY BATTERY COMPRISING THE SAME LG Chem, Ltd. (KR) 2010-03-03 EP claimed
WO-2009091227-A2 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2009-07-23 WO claimed
WO-2009091225-A2 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2009-07-23 WO claimed
WO-2008153296-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2008-12-18 WO claimed
EP-1350633-B1 Presensitized plate for making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2007-02-21 EP claimed
EP-1350633-A2 Presensitized plate for making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-10-08 EP claimed
EP-0598575-A2 Optical recording medium and production thereof CANON KABUSHIKI KAISHA (JP) 1994-05-25 EP claimed