Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243951 | 0.93 | ABL1 (0.37) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1282227 | 0.91 | ABL1 (0.36) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1282424 | 0.91 | ABL1 (0.37) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1282858 | 0.90 | ABL1 (0.39) | ABL1 | |
| SCHEMBL1283712 | 0.89 | AXL (0.36) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15260105 | 0.88 | MTOR (0.36) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1282153 | 0.88 | PIK3CD (0.41) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1283072 | 0.88 | ABL1 (0.35) | ABL1 | |
| SCHEMBL1282207 | 0.88 | ABL1 (0.40) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1282907 | 0.88 | ABL1 (0.36) | ABL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |