⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237247 | 0.86 | MEN1 (0.38) | — | |
| SCHEMBL10237268 | 0.85 | PTPN1 (0.49) | — | |
| SCHEMBL10237067 | 0.84 | PTPN1 (0.41) | — | |
| SCHEMBL10237267 | 0.84 | PTPN1 (0.41) | — | |
| SCHEMBL10236447 | 0.82 | — | — | |
| SCHEMBL10236463 | 0.82 | — | — | |
| SCHEMBL10237220 | 0.81 | PTPN1 (0.46) | — | |
| SCHEMBL10237270 | 0.81 | IGF2BP2 (0.45) | — | |
| SCHEMBL10279076 | 0.80 | — | — | |
| SCHEMBL10237244 | 0.79 | RXFP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193372-B2 | Phosphothiophene and phosphothiazole HCV polymerase inhibitors | IDENIX PHARMACEUTICALS, INC. (US) | 2012-06-05 | — | — | US | disclosed |