Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237263 | 0.92 | RXFP1 (0.49) | RXFP1MAPTTP53KDM4ENPSR1 | |
| SCHEMBL10237067 | 0.92 | PTPN1 (0.41) | — | |
| SCHEMBL10237218 | 0.89 | RXFP1 (0.48) | RXFP1MAPTKDM4ENPSR1 | |
| SCHEMBL10237256 | 0.88 | MAPT (0.55) | RXFP1MAPTTP53KDM4ENPSR1 | |
| SCHEMBL10237267 | 0.85 | PTPN1 (0.41) | — | |
| SCHEMBL10237244 | 0.85 | RXFP1 (0.44) | RXFP1MAPTTP53 | |
| SCHEMBL10279152 | 0.84 | MAPT (0.45) | RXFP1MAPTTP53 | |
| SCHEMBL10279684 | 0.84 | RXFP1 (0.46) | RXFP1MAPTTP53KDM4ENPSR1 | |
| SCHEMBL10237268 | 0.84 | PTPN1 (0.49) | — | |
| SCHEMBL10236447 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193372-B2 | Phosphothiophene and phosphothiazole HCV polymerase inhibitors | IDENIX PHARMACEUTICALS, INC. (US) | 2012-06-05 | — | — | US | disclosed |