SCHEMBL10239459

SCHEMBL10239459

C=C(C)OP1(=S)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)CC2O1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 19/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15865917 0.86 STING1 (0.54) STING1
SCHEMBL10185856 0.85 STING1 (0.42) STING1
SCHEMBL17824355 0.84 STING1 (0.74) STING1
SCHEMBL10239455 0.81 STING1 (0.64) STING1
SCHEMBL23477127 0.81 STING1 (0.77) STING1
SCHEMBL9926172 0.81 STING1 (0.77) STING1
SCHEMBL13341136 0.81 STING1 (0.77) STING1
SCHEMBL13341164 0.81 STING1 (0.77) STING1
SCHEMBL29885238 0.81 STING1 (0.77) STING1
SCHEMBL24852828 0.78 STING1 (0.57) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012088155-A1 CYCLIC NUCLEOTIDE ANALOGS ALIOS BIOPHARMA, INC. (US) 2012-06-28 — — WO disclosed
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