Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10240555 | 0.92 | ALOX5AP (0.83) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240402 | 0.91 | ALOX5AP (0.83) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240788 | 0.91 | ALOX5AP (0.77) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL725057 | 0.87 | ALOX5AP (1.00) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240659 | 0.86 | ALOX5AP (0.72) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240590 | 0.84 | ALOX5AP (0.77) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240549 | 0.83 | ALOX5AP (1.00) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240381 | 0.83 | ALOX5AP (0.82) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10240478 | 0.83 | ALOX5AP (1.00) | ALOX5APCYP2D6CYP2C9SLC6A3 | |
| SCHEMBL10242488 | 0.83 | ALOX5AP (0.78) | ALOX5APCYP2D6CYP2C9SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027322-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |