⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241118 | 0.87 | TSHR (0.37) | — | |
| SCHEMBL290165 | 0.83 | — | — | |
| SCHEMBL14947072 | 0.83 | — | — | |
| SCHEMBL26833 | 0.77 | TSHR (0.61) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.77 | — | — | |
| SCHEMBL329128 | 0.77 | TSHR (0.61) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL32889332 | 0.77 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.77 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.77 | — | — | |
| SCHEMBL36093 | 0.77 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| CN-111108109-A | Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors | 利奥制药有限公司 | 2020-05-05 | — | — | CN | claimed |
| EP-4741392-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | Shenzhen TargetRx Co., Ltd. (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-20260109698-A1 | MALT-1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2026-04-23 | — | — | US | disclosed |
| CN-116916924-B | MALT1 modulators and uses thereof | 稀有生物科学股份有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-119855821-A | Thiazolo [5,4-b ] pyridine MALT-1 inhibitors | 艾伯维公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119497712-A | Indane derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2025-02-21 | — | — | CN | disclosed |
| US-20250051327-A1 | MALT-1 MODULATORS | RECURSION PHARMACEUTICALS, INC. | 2025-02-13 | — | — | US | disclosed |
| WO-2025007863-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-119241532-A | 1H-pyrazolo [4,3-c ] pyridine compound, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | disclosed |
| EP-0313297-B1 | PROCESS FOR PRODUCTION OF AVERMECTIN AGLYCONES AND CULTURES THEREFOR | PFIZER INC. (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0276131-B1 | NON-NATURAL DEMETHYLAVERMECTINS AND PROCESS THEREFOR | PFIZER INC. (US) | 1993-04-07 | — | — | EP | disclosed |
| EP-0316124-B1 | ETHYLATED AVERMECTINS | PFIZER INC. (US) | 1993-04-07 | — | — | EP | disclosed |
| US-5077278-A | Parasiticides | PFIZER INC. (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0316124-A2 | Ethylated avermectins | PFIZER INC. (US) | 1989-05-17 | — | — | EP | disclosed |
| EP-0313297-A2 | Process for production of avermectin aglycones and cultures therefor | PFIZER INC. (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0284176-A2 | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0276103-A2 | Process for production of B avermectins and cultures therefor | PFIZER INC. (US) | 1988-07-27 | — | — | EP | disclosed |
| EP-0276131-A2 | Non-natural demethylavermectins and process therefor | PFIZER INC. (US) | 1988-07-27 | — | — | EP | disclosed |