SCHEMBL10240802

SCHEMBL10240802

Nc1ncc(-c2ccc(C3(c4noc(N5CCC(N)CC5)n4)CCC3)cc2)cn1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10240445 0.91 ALOX5AP (1.00) ALOX5AP
SCHEMBL10241293 0.91 ALOX5AP (1.00) ALOX5AP
SCHEMBL10241333 0.89 ALOX5AP (1.00) ALOX5AP
SCHEMBL11973113 0.88 ALOX5AP (0.78) ALOX5AP
SCHEMBL10240742 0.87 ALOX5AP (1.00) ALOX5AP
SCHEMBL724819 0.87 ALOX5AP (1.00) ALOX5AP
SCHEMBL11972619 0.87 ALOX5AP (1.00) ALOX5AP
SCHEMBL11972913 0.87 ALOX5AP (1.00) ALOX5AP
SCHEMBL10240786 0.84 ALOX5AP (0.91) ALOX5AP
SCHEMBL16592786 0.83 ALOX5AP (0.78) ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012027322-A1 OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-03-01 WO disclosed