SCHEMBL10241295

SCHEMBL10241295

Nc1ncc(-c2ccc(C3(c4noc(-c5cnc(C=O)cn5)n4)CCC3)cc2)cn1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10240387 0.87 ALOX5AP (0.76) ALOX5AP
SCHEMBL10240353 0.86 ALOX5AP (0.83) ALOX5AP
SCHEMBL10242485 0.85 ALOX5AP (0.73) ALOX5AP
SCHEMBL10240680 0.85 ALOX5AP (0.73) ALOX5AP
SCHEMBL16602694 0.84 ALOX5AP (0.69) ALOX5AP
SCHEMBL16592802 0.83 ALOX5AP (0.68) ALOX5AP
SCHEMBL10240568 0.83 ALOX5AP (0.71) ALOX5AP
SCHEMBL10240725 0.83 ALOX5AP (0.89) ALOX5AP
SCHEMBL10240495 0.83 ALOX5AP (0.74) ALOX5AP
SCHEMBL10240653 0.82 ALOX5AP (1.00) ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012027322-A1 OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-03-01 WO disclosed