Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412836 | 1.00 | CA12 (0.45) | CA12CA1CA2CA9EGFR | |
| SCHEMBL417692 | 1.00 | CA12 (0.45) | CA12CA1CA2CA9EGFR | |
| SCHEMBL412717 | 0.93 | CHRNA7 (0.48) | CA12CA1CA2CA9EGFR | |
| SCHEMBL10242564 | 0.93 | CHRNA7 (0.48) | CA12CA1CA2CA9EGFR | |
| SCHEMBL412716 | 0.93 | CHRNA7 (0.48) | CA12CA1CA2CA9EGFR | |
| SCHEMBL10204788 | 0.91 | CA12 (0.53) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10241399 | 0.90 | MEN1 (0.43) | CA12CA1CA2CA9EGFR | |
| SCHEMBL412357 | 0.90 | MEN1 (0.43) | CA12CA1CA2CA9EGFR | |
| SCHEMBL413178 | 0.90 | MEN1 (0.43) | CA12CA1CA2CA9EGFR | |
| SCHEMBL414696 | 0.90 | MEN1 (0.43) | CA12CA1CA2CA9EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |