Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10241602 | 0.85 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL10241609 | 0.85 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL10240716 | 0.83 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL10267113 | 0.79 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL10239953 | 0.79 | HCRTR2 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL2618728 | 0.78 | HCRTR1 (0.30) | HCRTR1HCRTR2 | |
| SCHEMBL10239715 | 0.76 | HCRTR2 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL10241601 | 0.74 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL10188722 | 0.69 | HCRTR2 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL9951705 | 0.69 | HCRTR2 (0.46) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165339-A1 | CYCLOPROPANE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165339-A1 | CYCLOPROPANE DERIVATIVES | HCRTR2, HCRTR1, CNR1 | HCRTR1 2/4885HCRTR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.