Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967697 | 0.83 | ESR1 (0.56) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL18403100 | 0.80 | ESR1 (0.52) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL11951853 | 0.80 | ESR1 (0.52) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL12995870 | 0.78 | ESR1 (0.61) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL12872219 | 0.77 | ESR1 (0.58) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL4634694 | 0.77 | ESR1 (0.78) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL5607941 | 0.76 | ESR1 (0.47) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL19056008 | 0.75 | ESR1 (0.56) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL23016793 | 0.73 | ESR1 (0.54) | ESR1CYP2C9TDP1LMNACYP1A2 | |
| SCHEMBL285683 | 0.73 | ESR1 (0.64) | ESR1CYP2C9TDP1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450746-A1 | Positive resist composition and pattern forming method using the composition | Fujifilm Corporation (JP) | 2012-05-09 | — | — | EP | disclosed |