Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 20/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243273 | 0.96 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10243270 | 0.94 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10243343 | 0.94 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10243206 | 0.91 | STAT3 (0.95) | STAT3 | |
| SCHEMBL10243386 | 0.90 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10243360 | 0.89 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10243184 | 0.89 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10244368 | 0.89 | STAT3 (1.00) | STAT3 | |
| SCHEMBL10243262 | 0.89 | STAT3 (1.00) | STAT3 | |
| SCHEMBL22920001 | 0.88 | STAT3 (0.88) | STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018868-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-02-09 | — | — | WO | disclosed |