SCHEMBL10249696

SCHEMBL10249696

NC(=O)c1ccc(I)c(I)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.58
LCK P06239 1/20 0.47
TSHR P16473 3/20 0.44
PARP10 Q53GL7 3/20 0.43
ALDH1A1 P00352 2/20 0.43
PARP15 Q460N3 2/20 0.43
PARP14 Q460N5 2/20 0.43
PARP4 Q9UKK3 2/20 0.43
KMT2A Q03164 1/20 0.43
PARP16 Q8N5Y8 1/20 0.43
PARP11 Q9NR21 1/20 0.43
HSD17B10 Q99714 2/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL858826 0.82 PARP1 (0.55) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL10962857 0.82 LCK (0.53) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL10594355 0.82 LCK (0.53) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL435829 0.82 PARP1 (0.55) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL1629983 0.82 PARP1 (0.50) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL3033308 0.81 PARP1 (0.40) PARP1TSHRCA2CA1TPMT
SCHEMBL29506358 0.80 MTOR (0.49) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL15539961 0.80 PARP1 (0.53) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL1233265 0.80 MTOR (0.49) PARP1LCKTSHRPARP10ALDH1A1
SCHEMBL2954394 0.80 PARP1 (0.49) PARP1LCKTSHRPARP10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250128220-A1 SYSTEMS WITH IMPROVED HYDROGEL FORMATION TIMES BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-04-24 US disclosed
WO-2025085642-A1 SYSTEMS WITH IMPROVED HYDROGEL FORMATION TIMES BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-04-24 WO disclosed
WO-2012012448-A1 METHODS OF TREATING BREAST CANCER USING 4-IODO-3-NITROBENZAMIDE IN COMBINATION WITH ANTI-TUMOR AGENTS BIPAR SCIENCES, INC. (US) 2012-01-26 WO disclosed