Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504730 | 0.94 | GRM5 (0.70) | GRM5 | |
| SCHEMBL504604 | 0.92 | GRM5 (0.81) | GRM5 | |
| SCHEMBL10253614 | 0.87 | GRM5 (0.74) | GRM5 | |
| SCHEMBL504565 | 0.84 | GRM5 (1.00) | GRM5 | |
| SCHEMBL10250307 | 0.84 | GRM5 (0.81) | GRM5 | |
| SCHEMBL504062 | 0.83 | GRM5 (0.81) | GRM5 | |
| SCHEMBL10250454 | 0.81 | GRM5 (0.66) | GRM5 | |
| SCHEMBL10250402 | 0.80 | GRM5 (0.64) | GRM5 | |
| SCHEMBL505016 | 0.79 | GRM5 (0.82) | GRM5 | |
| SCHEMBL504806 | 0.79 | GRM5 (0.89) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029190-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029190-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | GRM5, GRM2, GRM1 | GRM5 1/4885GPR119 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.