Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946942 | 0.84 | TSHR (0.56) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL16212370 | 0.83 | CYP3A4 (0.68) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL21402289 | 0.82 | TSHR (0.57) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL28410494 | 0.81 | TSHR (0.59) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL20000881 | 0.81 | TSHR (0.55) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL28578493 | 0.80 | CYP3A4 (0.72) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL178482 | 0.80 | TSHR (0.62) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL1682681 | 0.78 | GAA (0.77) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL18903256 | 0.78 | TSHR (0.53) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL5072122 | 0.78 | BCHE (0.73) | TSHRCYP3A4NFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413191-A1 | Actinic-ray- or radiation-sensitive resin composition, resist film therefrom and method of forming pattern therewith | Fujifilm Corporation (JP) | 2012-02-01 | — | — | EP | disclosed |