SCHEMBL10258458

SCHEMBL10258458

CO/N=C(\COc1ccc(COc2ccc(CCC(=O)O)c(N)c2)cc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.60
FFAR4 Q5NUL3 6/20 0.47
PTGER4 P35408 1/20 0.42
PTGER3 P43115 1/20 0.42
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433325 0.90 FFAR1 (0.62) FFAR1FFAR4PTGER4PTGER3AKR1B1
SCHEMBL433229 0.90 FFAR1 (0.62) FFAR1FFAR4
SCHEMBL433326 0.90 FFAR1 (0.62) FFAR1FFAR4PTGER4PTGER3AKR1B1
SCHEMBL10260790 0.90 FFAR1 (0.61) FFAR1FFAR4PTGER4PTGER3AKR1B1
SCHEMBL434057 0.89 FFAR1 (0.61) FFAR1FFAR4
SCHEMBL434058 0.89 FFAR1 (0.61) FFAR1FFAR4
SCHEMBL436123 0.89 FFAR1 (0.60) FFAR1FFAR4
SCHEMBL436122 0.89 FFAR1 (0.60) FFAR1FFAR4
SCHEMBL10258787 0.88 FFAR1 (0.59) FFAR1FFAR4
SCHEMBL15239313 0.88 FFAR1 (0.59) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012011125-A1 AGONISTS OF GPR40 CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) 2012-01-26 WO disclosed