⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102591 | 1.00 | — | — | |
| SCHEMBL13135822 | 1.00 | — | — | |
| Water SCHEMBL11497191 | 0.97 | — | — | |
| SCHEMBL12127833 | 0.92 | — | — | |
| SCHEMBL3455175 | 0.92 | — | — | |
| SCHEMBL15174483 | 0.90 | CYP2D6 (0.52) | — | |
| SCHEMBL1341663 | 0.90 | CYP2D6 (0.52) | — | |
| SCHEMBL15174081 | 0.90 | CYP2D6 (0.52) | — | |
| SCHEMBL15174509 | 0.90 | CYP2D6 (0.52) | — | |
| SCHEMBL22854103 | 0.90 | CYP2D6 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000863-A1 | USE OF NITROGEN HETEROCYCLIC COMPOUNDS AND RELATIVE COMPOSITIONS AS MICROBICIDES | NEED PHARMA S.R.L. (IT) | 2006-01-05 | — | — | WO | claimed |
| CN-111712492-B | Cyclotriazoles as LPA antagonists | 百时美施贵宝公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-110997644-B | Preparation of substituted 3-aryl-5-trifluoromethyl-1, 2, 4-oxadiazoles | 巴斯夫欧洲公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2022180080-A1 | ANTI-PROLIFERATIVE AGENTS | FIRST HEALTH PHARMACEUTICALS B.V. (NL) | 2022-09-01 | — | — | WO | disclosed |
| EP-4050002-A1 | ANTI-PROLIFERATIVE AGENTS | First Health Pharmaceuticals B.V. (NL) | 2022-08-31 | — | — | EP | disclosed |
| CN-111712492-A | Cyclohexaneacetic acid triazolazoles as LPA antagonists | 百时美施贵宝公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-110997644-A | Preparation of substituted 3-aryl-5-trifluoromethyl-1, 2, 4-oxadiazoles | 巴斯夫欧洲公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-2867230-B1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLES | MONSANTO TECHNOLOGY LLC (US) | 2020-02-12 | — | — | EP | disclosed |
| CN-104428296-B | Process for preparing 3, 5-disubstituted-1, 2, 4-oxadiazoles | 孟山都技术公司 | 2017-11-14 | — | — | CN | disclosed |
| US-9273037-B2 | Processes for the preparation of 3,5-disubstituted-1,2,4-oxadiazoles | MONSANTO TECHNOLOGY LLC (US) | 2016-03-01 | — | — | US | disclosed |
| US-5236916-A | Oxadiazinone substituted indole and benzimidazole derivatives | E. R. SQUIBB & SONS, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| US-5225408-A | Biphenyl oxadiazinone angiotensin II inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1993-07-06 | — | — | US | disclosed |
| WO-1993003726-A1 | MUSCARINIC AGONISTS | THE UNIVERSITY OF TOLEDO (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5187164-A | Psychological disorders, antiemetics | NOVO NORDISK A/S (DK) | 1993-02-16 | — | — | US | disclosed |
| US-5175166-A | Cognition activators | THE UNIVERSITY OF TOLEDO (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0515537-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-12-02 | — | — | EP | disclosed |
| US-5157160-A | Treatment of diseases of the nervous system | BEECHAM GROUP P.L.C. (GB) | 1992-10-20 | — | — | US | disclosed |
| US-5043343-A | Certain 5-substituted-1-aza-bicyclo[3.3.3]heptanes and their pharmaceutical compositions and methods | BEECHAM GROUP P.L.C. (GB) | 1991-08-27 | — | — | US | disclosed |
| WO-1991012254-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-08-22 | — | — | WO | disclosed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |