Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15239251 | 0.91 | FFAR1 (0.71) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL10258712 | 0.91 | FFAR1 (0.71) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL15239532 | 0.86 | FFAR1 (0.65) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL15239039 | 0.86 | FFAR1 (0.65) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL10259016 | 0.86 | FFAR1 (0.65) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL10259333 | 0.86 | FFAR1 (0.65) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL10262172 | 0.83 | FFAR1 (0.67) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL10267704 | 0.83 | FFAR1 (0.76) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL15239401 | 0.83 | FFAR1 (0.76) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL15239382 | 0.82 | FFAR1 (0.60) | FFAR1SMN1; SMN2RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |