⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21214912 | 1.00 | — | — | |
| SCHEMBL13899227 | 1.00 | — | — | |
| SCHEMBL19263829 | 1.00 | — | — | |
| SCHEMBL10260288 | 1.00 | — | — | |
| SCHEMBL12300420 | 1.00 | — | — | |
| SCHEMBL19263831 | 1.00 | — | — | |
| SCHEMBL12746267 | 1.00 | — | — | |
| SCHEMBL35361 | 1.00 | — | — | |
| SCHEMBL15298329 | 0.97 | — | — | |
| SCHEMBL13026644 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586729-B2 | Synthesis of decitabine | SCINOPHARM TAIWAN LTD. (TW) | 2013-11-19 | — | — | US | disclosed |
| US-8212021-B2 | Process for making 5-azacytosine nucleosides and their derivatives | SCINOPHARM TAIWAN, LTD. (TW) | 2012-07-03 | — | — | US | disclosed |
| US-20100087637-A1 | Synthesis of Decitabine | SCINOPHARM TAIWAN LTD. | 2010-04-08 | — | — | US | disclosed |
| US-20100036112-A1 | Process for Making 5-Azacytosine Nucleosides and Their Derivatives | SCINOPHARM TAIWAN LTD. | 2010-02-11 | — | — | US | disclosed |
| US-7598230-B2 | For the treatment of viral infections, microbial infections, and proliferative disorders; contain di- or triphosphate moeity mimetics, such as those containing boron anions | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2009-10-06 | — | — | US | disclosed |
| US-7285658-B2 | Nucleotide mimics and their prodrugs | BIOTA, INC. (US) | 2007-10-23 | — | — | US | disclosed |