Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9919779 | 0.89 | TLR7 (0.78) | TLR7NUDT1 | |
| SCHEMBL29386203 | 0.87 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL27721732 | 0.87 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL14368283 | 0.87 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL510344 | 0.87 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL43700 | 0.87 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL509587 | 0.87 | TLR7 (0.74) | TLR7NUDT1 | |
| SCHEMBL12175835 | 0.86 | TLR7 (0.64) | TLR7NUDT1 | |
| SCHEMBL12305197 | 0.86 | TLR7 (0.69) | TLR7 | |
| SCHEMBL509431 | 0.85 | TLR7 (0.72) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2510946-B1 | Conjugates of synthetic tlr agonists and uses therefor | UNIV CALIFORNIA (US) | 2015-08-05 | — | — | EP | disclosed |
| EP-2510946-A1 | Conjugates of synthetic tlr agonists and uses therefor | The Regents of The University of California (US) | 2012-10-17 | — | — | EP | disclosed |
| US-8211863-B2 | Administration of TLR7 ligands and prodrugs thereof for treatment of infection by hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2012-07-03 | — | — | US | disclosed |