Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15239260 | 0.88 | FFAR1 (0.71) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL10261127 | 0.88 | FFAR1 (0.71) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL15239262 | 0.88 | FFAR1 (0.71) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL10267703 | 0.87 | FFAR1 (0.61) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL22668240 | 0.86 | FFAR1 (0.68) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL22653335 | 0.86 | FFAR1 (0.68) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL15239373 | 0.85 | FFAR1 (0.67) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL22668535 | 0.85 | FFAR1 (0.67) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL10259528 | 0.85 | FFAR1 (0.67) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL22668061 | 0.85 | FFAR1 (0.61) | FFAR1SMN1; SMN2ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |