Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711417 | 0.84 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL696476 | 0.84 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL697270 | 0.84 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13711415 | 0.84 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13722165 | 0.82 | GSK3B (0.67) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13917087 | 0.80 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13722746 | 0.80 | GSK3B (0.64) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13723194 | 0.80 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13711419 | 0.79 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL697014 | 0.79 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423207-A2 | 2-(cyclic amino)-pyrimidone derivatives as TPK1 inhibitors | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |