Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737125 | 0.84 | CYP4F2 (0.43) | CYP4F2CYP4A11POLBPKMKMT2A | |
| SCHEMBL22098179 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL8071102 | 0.82 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL186582 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL1106769 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL186204 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL187550 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL798044 | 0.79 | CYP4F2 (0.53) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL24525804 | 0.79 | CYP4F2 (0.54) | CYP4F2CYP4A11LMNAPOLBPKM | |
| SCHEMBL1660144 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11LMNAPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |