Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 8/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180988 | 0.94 | ACACB (0.46) | ACACBACACACNR2CNR1TRPA1 | |
| SCHEMBL19678200 | 0.89 | FFAR4 (0.42) | ACACBACACACNR2CNR1FFAR4 | |
| SCHEMBL19678203 | 0.89 | FFAR4 (0.42) | ACACBACACACNR2CNR1FFAR4 | |
| SCHEMBL19678206 | 0.89 | ACACB (0.42) | ACACBACACAKIF11FFAR4 | |
| SCHEMBL12909444 | 0.87 | ACACB (0.49) | ACACBACACACNR2CNR1TAAR1 | |
| SCHEMBL2737106 | 0.86 | ACACB (0.46) | ACACBACACACNR1TRPA1KIF11 | |
| SCHEMBL19678187 | 0.86 | ACACB (0.39) | ACACBACACATRPA1RIPK1KIF11 | |
| SCHEMBL12092678 | 0.85 | ACACB (0.38) | ACACBACACATRPA1RIPK1KIF11 | |
| SCHEMBL19678166 | 0.84 | ACACB (0.43) | ACACBACACACNR2CNR1TRPA1 | |
| SCHEMBL19678190 | 0.84 | ACACB (0.37) | ACACBACACARIPK1KIF11CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |