Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 20/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327218 | 0.88 | S1PR5 (0.66) | S1PR5S1PR3S1PR1 | |
| Hydrochloric Acid SCHEMBL327009 | 0.87 | S1PR5 (0.66) | S1PR5S1PR3S1PR1 | |
| SCHEMBL325721 | 0.82 | S1PR5 (0.52) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10265157 | 0.81 | S1PR5 (0.45) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10265761 | 0.81 | S1PR5 (0.50) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10264826 | 0.76 | S1PR5 (0.62) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10268792 | 0.76 | S1PR5 (0.62) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10264933 | 0.76 | S1PR5 (0.75) | S1PR5S1PR3S1PR1 | |
| Hydrochloric Acid SCHEMBL323118 | 0.76 | S1PR5 (0.63) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10265821 | 0.75 | S1PR5 (0.62) | S1PR5S1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004378-A1 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | ABBOTT HEALTHCARE PRODUCTS B.V. (NL) | 2012-01-12 | — | — | WO | disclosed |