Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 20/20 | 0.75 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264933 | 0.93 | S1PR5 (0.75) | S1PR5S1PR3S1PR1 | |
| SCHEMBL326331 | 0.86 | S1PR5 (1.00) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10268691 | 0.86 | S1PR5 (0.63) | S1PR5S1PR3S1PR1 | |
| Hydrochloric Acid SCHEMBL15136998 | 0.85 | S1PR5 (0.98) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10265371 | 0.85 | S1PR5 (0.58) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10268690 | 0.84 | S1PR5 (0.78) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10265683 | 0.83 | S1PR5 (0.58) | S1PR5S1PR3S1PR1 | |
| SCHEMBL18537185 | 0.83 | S1PR5 (0.67) | S1PR5S1PR3S1PR1 | |
| SCHEMBL327014 | 0.81 | S1PR5 (0.77) | S1PR5S1PR3S1PR1 | |
| SCHEMBL10264921 | 0.80 | S1PR5 (0.54) | S1PR5S1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004378-A1 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS | ABBOTT HEALTHCARE PRODUCTS B.V. (NL) | 2012-01-12 | — | — | WO | disclosed |