Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620885 | 0.85 | SCD (0.38) | SCDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL621050 | 0.83 | MAPT (0.40) | SCDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31670265 | 0.83 | MAPT (0.40) | SCDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL620900 | 0.82 | SCD (0.39) | SCDMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10250650 | 0.82 | MAPT (0.42) | SCDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL627249 | 0.81 | MEN1 (0.37) | SCDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL620499 | 0.80 | KDM4E (0.40) | SCDMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL618152 | 0.80 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10251225 | 0.79 | MAPT (0.42) | SCDMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL627405 | 0.79 | SMPD1 (0.38) | SCDMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |