Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15238998 | 0.92 | FFAR1 (0.54) | FFAR1HPGDPPARARAB9ASMN1; SMN2 | |
| SCHEMBL10258499 | 0.92 | FFAR1 (0.54) | FFAR1HPGDPPARARAB9ASMN1; SMN2 | |
| SCHEMBL435616 | 0.90 | FFAR1 (0.49) | FFAR1HPGDPPARARAB9ASMN1; SMN2 | |
| SCHEMBL435615 | 0.90 | FFAR1 (0.49) | FFAR1HPGDPPARARAB9ASMN1; SMN2 | |
| SCHEMBL435215 | 0.89 | FFAR1 (0.55) | FFAR1HPGDPPARARAB9ASMN1; SMN2 | |
| SCHEMBL435216 | 0.89 | FFAR1 (0.55) | FFAR1HPGDPPARARAB9ASMN1; SMN2 | |
| SCHEMBL435519 | 0.88 | FFAR1 (0.54) | FFAR1HPGDPPARAPPARGPPARD | |
| SCHEMBL435518 | 0.88 | FFAR1 (0.54) | FFAR1HPGDPPARAPPARGPPARD | |
| SCHEMBL10258787 | 0.83 | FFAR1 (0.59) | FFAR1PPARAPPARGPPARDFFAR4 | |
| SCHEMBL15239313 | 0.83 | FFAR1 (0.59) | FFAR1PPARAPPARGPPARDFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |