Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 10/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987495 | 0.88 | PPARA (0.53) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL4537123 | 0.87 | PPARA (0.44) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL11540350 | 0.83 | PPARA (0.49) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL25463419 | 0.77 | AR (0.39) | PPARACYP1A2CYP3A4MEN1MAPT | |
| Sulfamate SCHEMBL9451429 | 0.77 | PPARA (0.47) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL8037406 | 0.77 | PPARA (0.65) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL11749176 | 0.76 | MAOB (0.55) | KMT2APPARGNPSR1LMNA | |
| Hydrochloric Acid SCHEMBL10971211 | 0.76 | PPARA (0.63) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL18016873 | 0.74 | PPARA (0.46) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL11459281 | 0.73 | MEN1 (0.50) | PPARACYP1A2CYP2C19MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012063085-A2 | DRUG DERIVATIVES | REDX PHARMA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |