Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270983 | 0.88 | BACE1 (0.75) | BACE1APP | |
| SCHEMBL10270999 | 0.86 | BACE1 (0.72) | BACE1APP | |
| SCHEMBL9948258 | 0.81 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL10270442 | 0.79 | APP (0.70) | BACE1APP | |
| SCHEMBL9947940 | 0.78 | APP (1.00) | BACE1APP | |
| SCHEMBL18562885 | 0.78 | BACE1 (0.93) | BACE1APP | |
| SCHEMBL9948350 | 0.76 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL10271132 | 0.74 | BACE1 (0.80) | BACE1APP | |
| SCHEMBL9948078 | 0.74 | APP (1.00) | BACE1APP | |
| SCHEMBL16621516 | 0.74 | BACE1 (1.00) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087237-A1 | COMPOUNDS AND THEIR USE AS BACE INHIBITORS | ASTRAZENECA AB (SE) | 2012-06-28 | — | — | WO | disclosed |