SCHEMBL10271670

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8185505	1.00	PDE4B (0.46)	PDE4BOPRM1OPRD1OGFRL1OPRK1
	SCHEMBL10271617	0.95	PDE4B (0.41)	PDE4BOPRM1OPRD1OGFRL1OPRK1
	SCHEMBL3023140	0.90	PDE4B (0.47)	PDE4BACVR1AXLMERTKTP53
	SCHEMBL10272053	0.90	PARP1 (0.38)	PDE4BPARP1PARP2AKT1AXL
	SCHEMBL8193271	0.90	PARP1 (0.38)	PDE4BPARP1PARP2AKT1AXL
	SCHEMBL10271898	0.90	PDE4B (0.47)	PDE4BPARP1PARP2AKT1TP53
	SCHEMBL10271668	0.89	PARP1 (0.39)	PDE4BPARP1PARP2AKT1ACVR1
	SCHEMBL8168986	0.89	PARP1 (0.39)	PDE4BPARP1PARP2AKT1ACVR1
	SCHEMBL8179028	0.88	PDE4B (0.48)	PDE4BPARP1PARP2JAK1PDE4D
	SCHEMBL871460	0.87	PDE4B (0.51)	PDE4BACVR1AXLMERTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.