SCHEMBL10272033

SCHEMBL10272033

CCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.77
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2D6 P10635 2/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2C19 P33261 2/20 0.60
ABCB11 O95342 1/20 0.57
F2 P00734 1/20 0.57
ST14 Q9Y5Y6 1/20 0.57
CYP2J2 P51589 1/20 0.52
GRM2 Q14416 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7723895 1.00 F10 (0.77) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL7723004 1.00 F10 (0.77) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13738881 0.88 F10 (0.79) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13739376 0.88 F10 (0.79) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13838775 0.88 F10 (0.79) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL455331 0.87 F10 (0.77) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15203246 0.87 F10 (1.00) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL21278838 0.87 F10 (0.77) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL455330 0.87 F10 (0.77) F10CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13738628 0.87 F10 (0.77) F10CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705028-B1 PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2019-08-21 EP disclosed
WO-2012051692-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2012-04-26 WO disclosed
US-20100273798-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2010-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100273798-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF CYP2C9, F2, F9 F10 8/4885CYP1A2 18/4885CYP3A4 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.