Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717620 | 0.92 | SYK (0.43) | SYK | |
| SCHEMBL2717624 | 0.92 | SYK (0.43) | SYK | |
| SCHEMBL2718647 | 0.90 | SYK (0.40) | SYK | |
| SCHEMBL10271724 | 0.88 | SYK (0.52) | SYK | |
| SCHEMBL10271911 | 0.86 | SYK (0.54) | SYK | |
| SCHEMBL2729456 | 0.85 | SYK (0.65) | SYK | |
| SCHEMBL2729451 | 0.85 | SYK (0.65) | SYK | |
| SCHEMBL10272190 | 0.85 | SYK (0.63) | SYK | |
| SCHEMBL2728643 | 0.83 | SYK (0.48) | SYK | |
| SCHEMBL2728647 | 0.83 | SYK (0.48) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061415-A1 | OXYPYRIMIDINES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |