⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295801 | 0.70 | — | — | |
| SCHEMBL28515944 | 0.70 | — | — | |
| SCHEMBL21683047 | 0.70 | — | — | |
| Methylene Chloride SCHEMBL28160336 | 0.67 | — | — | |
| SCHEMBL8712429 | 0.67 | — | — | |
| SCHEMBL6040398 | 0.67 | — | — | |
| Methylene Chloride SCHEMBL28158615 | 0.65 | — | — | |
| Ethyl Chloride SCHEMBL28420393 | 0.64 | — | — | |
| SCHEMBL1906553 | 0.63 | — | — | |
| SCHEMBL3609929 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020439-B1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC (JP) | 2006-08-30 | — | — | EP | claimed |
| EP-0883620-B1 | PROCESS FOR THE PREPARATION OF 2-HALOMETHYL-PENEMS AND THEIR USE FOR THE PREPARATION OF ANTIBACTERIAL PENEMS | MENARINI FARMA IND (IT) | 2002-09-04 | — | — | EP | claimed |
| US-6153747-A | Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 2000-11-28 | — | — | US | claimed |
| EP-0883620-A1 | PROCESS FOR THE PREPARATION OF 2-HALOMETHYL-PENEMS AND THEIR USE FOR THE PREPARATION OF ANTIBACTERIAL PENEMS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031922-A1 | PROCESS FOR THE PREPARATION OF 2-HALOMETHYL-PENEMS AND THEIR USE FOR THE PREPARATION OF ANTIBACTERIAL PENEMS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1997-09-04 | — | — | WO | claimed |
| US-20190142805-A1 | Novel Compounds and Compositions and Methods of Use | ARDEA BIOSCIENCES INC. | 2019-05-16 | — | — | US | disclosed |
| US-10183012-B2 | Compounds and compositions and methods of use | ARDEA BIOSCIENCES, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-20170281601-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20160221970-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. | 2016-08-04 | — | — | US | disclosed |
| EP-2842948-A1 | Novel compounds and compositions and methods of use | Ardea Biosciences, Inc. (US) | 2015-03-04 | — | — | EP | disclosed |
| EP-2217577-B1 | NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC (US) | 2014-08-06 | — | — | EP | disclosed |
| US-20140005136-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. (US) | 2014-01-02 | — | — | US | disclosed |
| WO-2006033742-A2 | ENGINEERED ANTIBODY FRAGMENT THAT IRREVERSIBLY BINDS AN ANTIGEN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20040158031-A1 | Alicyclic compound for optical material | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1398317-A1 | ALICYCLIC COMPOUND FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6452006-B1 | USED AS INTERMEDIATE IN THE SYNTHESIS OF ACTIVE COMPOUNDS WHICH ARE INHIBITORS OF HIV (HUMAN IMMUNODEFICIENCY VIRUS) REVERSE TRANSCRIPTASE | SYLACHIM (FR) | 2002-09-17 | — | — | US | disclosed |
| EP-0193700-B1 | HERBICIDALLY ACTIVE SUBSTITUTED BENZISOXAZOLE (OR BENZISOTHIAZONE) COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4738709-A | Herbicidally active substituted benzisoxazoles | PPG INDUSTRIES, INC. (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0193700-A1 | Herbicidally active substituted benzisoxazole (or benzisothiazone) compounds | PPG INDUSTRIES, INC. (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4093625-A | 6-Sulfur analogs of penicillins and cephalosporins | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1978-06-06 | — | — | US | disclosed |