Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527311 | 0.91 | CYP17A1 (0.75) | CYP17A1SLC22A12 | |
| SCHEMBL526682 | 0.80 | CYP17A1 (0.70) | CYP17A1 | |
| SCHEMBL526757 | 0.79 | CYP17A1 (0.81) | CYP17A1SLC22A12 | |
| SCHEMBL526661 | 0.78 | CYP17A1 (0.74) | CYP17A1 | |
| SCHEMBL527076 | 0.77 | CYP17A1 (1.00) | CYP17A1 | |
| SCHEMBL526423 | 0.75 | CYP17A1 (0.92) | CYP17A1 | |
| SCHEMBL527398 | 0.74 | CYP17A1 (0.65) | CYP17A1SLC22A12 | |
| SCHEMBL10272857 | 0.74 | CYP17A1 (0.77) | CYP17A1SLC22A12 | |
| SCHEMBL526698 | 0.73 | CYP17A1 (0.77) | CYP17A1SLC22A12 | |
| SCHEMBL527307 | 0.72 | CYP17A1 (0.73) | CYP17A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015723-A1 | SULFONAMIDE COMPOUNDS USEFUL AS CYP17 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-02 | — | — | WO | disclosed |