Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 18/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272889 | 0.88 | CYP17A1 (0.51) | CYP17A1 | |
| SCHEMBL10272890 | 0.88 | CYP17A1 (0.54) | CYP17A1 | |
| SCHEMBL526683 | 0.87 | CYP17A1 (0.53) | CYP17A1 | |
| SCHEMBL10272892 | 0.87 | CYP17A1 (0.69) | CYP17A1 | |
| SCHEMBL527370 | 0.80 | CYP17A1 (0.76) | CYP17A1 | |
| SCHEMBL10272855 | 0.79 | CYP17A1 (0.56) | CYP17A1 | |
| SCHEMBL10272888 | 0.77 | CYP17A1 (0.62) | CYP17A1 | |
| SCHEMBL526673 | 0.76 | CYP17A1 (0.56) | CYP17A1 | |
| SCHEMBL527548 | 0.76 | CYP17A1 (0.53) | CYP17A1 | |
| SCHEMBL527271 | 0.76 | CYP17A1 (0.50) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015723-A1 | SULFONAMIDE COMPOUNDS USEFUL AS CYP17 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-02 | — | — | WO | disclosed |