Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | SHBG | P04278 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274137 | 1.00 | MEN1 (0.74) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL10274435 | 1.00 | MEN1 (0.74) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL13160896 | 1.00 | MEN1 (0.74) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL15274236 | 1.00 | MEN1 (0.74) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL13630725 | 1.00 | MEN1 (0.74) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL10273598 | 1.00 | MEN1 (0.74) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL15369418 | 0.93 | MEN1 (0.64) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL10274139 | 0.93 | MEN1 (0.64) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL10273925 | 0.93 | MEN1 (0.64) | MEN1KMT2ASHBGPOLBMAPK1 | |
| SCHEMBL10274338 | 0.93 | MEN1 (0.64) | MEN1KMT2ASHBGPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083112-A2 | CYP11B, CYP17, AND/OR CYP21 INHIBITORS | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-06-21 | — | — | WO | disclosed |