⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502844 | 1.00 | — | — | |
| SCHEMBL13210700 | 0.78 | — | — | |
| SCHEMBL1686186 | 0.76 | GAA (0.35) | — | |
| SCHEMBL28147361 | 0.76 | — | — | |
| SCHEMBL12885915 | 0.73 | — | — | |
| SCHEMBL13103869 | 0.73 | — | — | |
| SCHEMBL2606457 | 0.72 | — | — | |
| SCHEMBL1244002 | 0.72 | — | — | |
| SCHEMBL2606459 | 0.72 | — | — | |
| SCHEMBL22838179 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415358-B | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3448856-B1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF ROR GAMMA T | JANSSEN PHARMACEUTICA NV (BE) | 2022-01-05 | — | — | EP | disclosed |
| US-20210221804-A1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF RORyT | JANSSEN PHARMACEUTICA NV (BE) | 2021-07-22 | — | — | US | disclosed |
| US-20210198251-A1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF RORyT | JANSSEN PHARMACEUTICA NV (BE) | 2021-07-01 | — | — | US | disclosed |
| US-20210188836-A1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF RORyT | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | US | disclosed |
| US-10975068-B2 | 6-aminopyridin-3-yl thiazoles as modulators of RORγT | JANSSEN PHARMACEUTICA NV (BE) | 2021-04-13 | — | — | US | disclosed |
| WO-2017189661-A1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF RORγT | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-02 | — | — | WO | disclosed |
| US-20170313691-A1 | 6-AMINOPYRIDIN-3-YL THIAZOLES AS MODULATORS OF RORyT | JANSSEN PHARMACEUTICA NV (BE) | 2017-11-02 | — | — | US | disclosed |
| US-8952185-B2 | Production method of optically active dihydrobenzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8318117-B2 | Absorption medium and method for removing sour gases from fluid streams, in particular from flue gases | BASF SE (DE) | 2012-11-27 | — | — | US | disclosed |
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20110135549-A1 | ABSORPTION MEDIUM AND METHOD FOR REMOVING SOUR GASES FROM FLUID STREAMS, IN PARTICULAR FROM FLUE GASES | BASF SE (DE) | 2011-06-09 | — | — | US | disclosed |