SCHEMBL10276971

SCHEMBL10276971

O=C(O)CCCCCCCCCCc1ccc(Br)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.69
RXFP1 Q9HBX9 1/20 0.69
HDAC1 Q13547 2/20 0.57
HDAC2 Q92769 2/20 0.57
HDAC3 O15379 1/20 0.57
MAPK1 P28482 1/20 0.57
ADRA1A P35348 1/20 0.57
HDAC4 P56524 1/20 0.57
SLC6A3 Q01959 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HDAC7 Q8WUI4 1/20 0.57
HDAC10 Q969S8 1/20 0.57
HDAC11 Q96DB2 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
HDAC9 Q9UKV0 1/20 0.57
HDAC5 Q9UQL6 1/20 0.57
FFAR1 O14842 1/20 0.54
FFAR4 Q5NUL3 1/20 0.54
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9859814 1.00 MAPT (0.69) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL16136610 1.00 MAPT (0.69) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL25176127 1.00 MAPT (0.69) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL29831093 1.00 MAPT (0.69) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1114650 0.98 MAPT (0.66) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1857558 0.92 HDAC1 (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
Hydrochloric Acid SCHEMBL3866368 0.90 SMN1; SMN2 (0.64) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL3814880 0.90 MAPT (0.83) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL9671779 0.90 MAPT (0.83) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL7827144 0.88 MAPT (0.80) MAPTRXFP1HDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10654880-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI HUI (TW) 2020-05-19 US disclosed
US-10654880-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI HUI (TW) 2020-05-19 US disclosed
EP-2661440-B1 METHOD FOR THE PREPARATION OF GLYCOSPHINGOLIPIDS UNIV NAT TAIWAN (TW) 2017-09-27 EP disclosed
EP-2661440-B1 METHOD FOR THE PREPARATION OF GLYCOSPHINGOLIPIDS UNIV NAT TAIWAN (TW) 2017-09-27 EP disclosed
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF LIANG PI-HUI (TW) 2016-08-11 US disclosed
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF LIANG PI-HUI (TW) 2016-08-11 US disclosed
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF LIANG PI-HUI (TW) 2016-08-11 US disclosed
US-9181292-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI-HUI (TW) 2015-11-10 US disclosed
US-9181292-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI-HUI (TW) 2015-11-10 US disclosed
US-9181292-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI-HUI (TW) 2015-11-10 US disclosed
EP-2661440-A2 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF National Taiwan University (TW) 2013-11-13 EP disclosed
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 US disclosed
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 US disclosed
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 US disclosed
WO-2012094540-A2 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF UGCG, CERS2, SGMS1 MAPT 2929/4885RXFP1 4469/4885HDAC1 1434/4885
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF UGCG, CERS2, SGMS1 MAPT 2929/4885RXFP1 4469/4885HDAC1 1434/4885
US-10654880-B2 Methods for preparation of glycosphingolipids and uses thereof UGCG, CERS2, SGMS1 MAPT 2929/4885RXFP1 4469/4885HDAC1 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.