Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25222155 | 0.87 | KMT2A (0.53) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL1707681 | 0.87 | KMT2A (0.79) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL11851842 | 0.81 | KMT2A (0.70) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL13326955 | 0.81 | KMT2A (1.00) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL24962264 | 0.81 | HRH4 (0.56) | KMT2ANPSR1HRH4MEN1 | |
| SCHEMBL11898909 | 0.79 | KMT2A (0.68) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL5480430 | 0.79 | KMT2A (0.68) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL11960321 | 0.77 | KMT2A (0.64) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL10847885 | 0.76 | KMT2A (0.62) | KMT2AALDH1A1NPSR1HRH4LMNA | |
| SCHEMBL24394696 | 0.74 | KMT2A (0.60) | KMT2AALDH1A1NPSR1HRH4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035039-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-22 | — | — | WO | disclosed |