Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1910769 | 0.91 | MEN1 (0.33) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL10278802 | 0.85 | KMT2A (0.36) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL10278807 | 0.85 | KMT2A (0.36) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL320452 | 0.85 | KMT2A (0.36) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL10278926 | 0.82 | HTT (0.34) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL1910819 | 0.82 | MEN1 (0.34) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL14902733 | 0.81 | MEN1 (0.37) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL14902763 | 0.80 | MEN1 (0.34) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL1911110 | 0.78 | MEN1 (0.37) | MEN1KMT2AHTTMAPTPOLB | |
| SCHEMBL1910770 | 0.76 | MEN1 (0.33) | MEN1KMT2AHTTMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109682-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2013-05-02 | — | — | US | disclosed |
| US-20130109682-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2013-05-02 | — | — | US | disclosed |
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109682-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | PIM1, GSK3A, GSK3B | MEN1 2862/4885KMT2A 691/4885HTT 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.