Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 17/20 | 0.53 |
| ▸ | TYK2 | P29597 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470300 | 0.93 | TTK (0.53) | TTKTYK2PDE4D | |
| SCHEMBL470050 | 0.92 | TTK (0.51) | TTK | |
| SCHEMBL470291 | 0.92 | TTK (0.52) | TTKTYK2PDE4D | |
| SCHEMBL10279715 | 0.91 | TTK (0.55) | TTK | |
| SCHEMBL469960 | 0.91 | TTK (0.54) | TTKTYK2PDE4D | |
| SCHEMBL470292 | 0.89 | TTK (0.57) | TTKTYK2PDE4D | |
| SCHEMBL457096 | 0.88 | TTK (0.68) | TTK | |
| SCHEMBL10279100 | 0.88 | TTK (0.51) | TTKTYK2PDE4D | |
| SCHEMBL10279268 | 0.88 | TTK (0.59) | TTK | |
| SCHEMBL10279103 | 0.88 | TTK (0.54) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |