Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765470 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL1504009 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL3338646 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL3308688 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL765158 | 0.92 | MLLT1 (0.47) | RAB9ANPC1POLBGHSRMEN1 | |
| SCHEMBL10476595 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL1503872 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL763991 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL10476645 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL | |
| SCHEMBL10476677 | 0.92 | MEN1 (0.53) | RAB9AMEN1KMT2AATMPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |