Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881994 | 0.85 | POLB (0.52) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL800189 | 0.84 | POLB (0.54) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL881945 | 0.81 | POLB (0.44) | POLBKMT2AMEN1USP2P2RY12 | |
| SCHEMBL7033257 | 0.78 | POLB (0.68) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL14428954 | 0.76 | POLB (0.58) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL15691498 | 0.76 | POLB (0.56) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL16904883 | 0.76 | POLB (0.57) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL12404755 | 0.76 | P2RY6 (0.59) | POLBP2RY6P2RY14NT5EABL1 | |
| Phosphoric Acid SCHEMBL22498821 | 0.75 | P2RY6 (0.56) | POLBP2RY6P2RY14NT5EABL1 | |
| SCHEMBL13396551 | 0.75 | POLB (0.64) | POLBP2RY6P2RY14NT5EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040126-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-29 | — | — | WO | disclosed |