Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.34 |
| ▸ | CDK9 | P50750 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364797 | 0.92 | MEN1 (0.45) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL366946 | 0.77 | MEN1 (0.48) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL20862871 | 0.76 | CA1 (0.44) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL10227457 | 0.73 | CA1 (0.41) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL28883279 | 0.73 | CA1 (0.50) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL10177309 | 0.70 | MEN1 (0.44) | MEN1KMT2ACCNT1CDK9ALDH1A1 | |
| SCHEMBL19643364 | 0.69 | NPSR1 (0.40) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL10280962 | 0.68 | MEN1 (0.35) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL365135 | 0.68 | MEN1 (0.50) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL366679 | 0.68 | MEN1 (0.41) | MEN1KMT2AALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |