Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 11/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1024199 | 0.99 | ACKR3 (0.37) | ACKR3IL2GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL1028346 | 0.94 | ACKR3 (0.37) | ACKR3IL2GRIN1GRIN2B | |
| SCHEMBL1025864 | 0.92 | ACKR3 (0.36) | ACKR3IL2GRIN1GRIN2B | |
| SCHEMBL1028136 | 0.92 | IL2 (0.38) | ACKR3IL2GRIN1GRIN2BGAA | |
| Hydrochloric Acid SCHEMBL1027482 | 0.91 | ACKR3 (0.36) | ACKR3IL2GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL1025536 | 0.91 | IL2 (0.37) | ACKR3IL2GRIN1GRIN2BGAA | |
| SCHEMBL1025983 | 0.86 | ACKR3 (0.42) | ACKR3IL2GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL1027454 | 0.86 | ACKR3 (0.36) | ACKR3 | |
| Hydrochloric Acid SCHEMBL1026783 | 0.85 | IL2 (0.36) | ACKR3IL2GRIN1GRIN2BGAA | |
| Hydrochloric Acid SCHEMBL1025954 | 0.85 | ACKR3 (0.36) | ACKR3IL2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |